Tissue characteristics of the athlete"s heart: differentiation of physiological and pathological hypertrophy using parametric T1 and T2 mapping

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main source(s): Research, Development and Innovation Fund Hungary Background Intensive physical exercise leads to structural functional cardiac adaptation termed athlete’s heart. Cardiac magnetic resonance (CMR) has an important role in the differentiation physiological pathological conditions. Beside precise measurement ventricular volumes, mass, function, it provides tissue specific information. Recently, native T1 mapping technique been applied as a non-contrast method detect myocardial fibrosis. Previous studies suggested that can identify pathology before other CMR imaging techniques. T2 values are elevated case edema. Purpose The aim our study was investigate differences characteristics especially highly trained healthy athletes, controls patients with hypertrophic cardiomyopathy (HCM). Methods A total 43 athletes (water polo, swimming, football, 22 ± 8 training hours/week), 27 non-athlete control 25 HCM were involved study. Our inclusion criteria were: age >18 years, athlete group >7 hours per week . We evaluated left (LV) end-systolic, end-diastolic (EDVi) stroke volume (SVi) index, mass index (LVMi), ejection fraction (EF) maximal wall thickness (EDWT). In basal short axis slice evaluated. Results Athletes had significantly higher LV volumes compared (LVEDVi 114 13 vs. 86 11; 84 15 ml/m2, LVSVi 64 7 51 7; 54 10 respectively, p < 0.0001). highest LVMi (72 14 g/m2) EDWT (18 4 mm) controls, (60 11 42 (10 2 1 (p 0.001). differed three groups, lowest, (athletes: 956 19 ms, controls: 971 20 patients: 993 39 ms; There no difference between (44 ms), (45 ms) two groups 0.01). Conclusion regular may lead changes myocardium. potentially useful tools for differentiating athlete"s heart cardiomyopathy. Figure.